TL;DR:
- Azithromycin DT is a delayed‑release tablet of the antibiotic azithromycin, used for infections like bronchitis and chlamydia.
- Typical adult regimen: 500mg on day1, then 250mg daily for four more days.
- Common side effects include stomach upset, mild headache and temporary changes in taste.
- Take the tablet with a full glass of water, on an empty stomach unless your doctor says otherwise.
- If you miss a dose, take it as soon as you remember unless it’s almost time for the next one.
What is Azithromycin DT?
Azithromycin is a macrolide antibiotic that stops bacteria from growing. The "DT" stands for delayed‑release, meaning the tablet dissolves slower than a regular tablet. This design keeps the drug in your system a bit longer, allowing a shorter overall course for many infections.
In Australia, the most common brand names are Zithromax DT and similar generic versions. Doctors prescribe it for respiratory tract infections, ear infections, skin infections and some sexually transmitted infections. Because it stays in the body longer, you usually finish the whole pack even if you feel better after a couple of days.
When and How to Take It
Getting the dosage right is crucial. Below is the standard schedule for adults and kids over 12kg. Your doctor may adjust it based on the infection type, kidney function or other meds you’re taking.
Age / Weight | Day1 (Loading Dose) | Days2‑5 (Maintenance) |
---|---|---|
Adults (≥18yr) | 500mg (1 tablet) | 250mg (½ tablet) once daily |
Kids 12kg‑40kg | 10mg/kg (≈1 tablet) | 5mg/kg (≈½ tablet) once daily |
Kids >40kg | 500mg (1 tablet) | 250mg (½ tablet) once daily |
Key reminders:
- Swallow the tablet whole - don’t split or chew it unless the label says it’s safe.
- Take it on an empty stomach (at least 30minutes before a meal) for best absorption.
- Finish the full course, even if symptoms subside.
- If you’re on antacids containing aluminum or magnesium, wait two hours after taking the tablet.
Missing a dose? Take it as soon as you remember, unless the next dose is due within a few hours. In that case, skip the missed one - don’t double up.

Common Side Effects and Safety Tips
Like any medication, Azithromycin DT can cause unwanted effects. Most are mild and go away on their own, but it helps to know what to expect.
- Gastrointestinal upset: nausea, mild diarrhea or stomach cramps are the most frequent complaints.
- Headache or mild dizziness - usually fleeting.
- Temporary change in taste or a metallic feeling in the mouth.
- Skin rash or itching - stop the drug and call your doctor if it spreads.
Serious but rare reactions include:
- Allergic reactions such as swelling of the face, lips or throat.
- Heart rhythm changes (QT prolongation) - more likely if you take other QT‑affecting meds.
- Liver enzyme elevations - your doctor may ask for blood tests if you have liver disease.
Safety checklist:
- Tell your pharmacist about any other meds, especially heart drugs, blood thinners or other antibiotics.
- If you’re pregnant or breastfeeding, discuss risks with your GP - most data suggest it’s safe after the first trimester, but a professional’s opinion is essential.
- Don’t use if you’ve had a severe reaction to macrolide antibiotics before.
- Store tablets at room temperature, away from moisture and heat.
Frequently Asked Questions
Here are the questions people ask most about Azithromycin DT.
- Can I take Azithromycin DT with alcohol? A small amount of alcohol won’t affect the drug, but heavy drinking may worsen stomach upset.
- Is it safe for children? Yes, for kids over 12kg the dosage is weight‑based. Never give it to infants under 6months without a doctor’s order.
- How long does it stay in my system? The drug’s half‑life is about 68hours, so it can be detected for up to a week after the last dose.
- Can I drive after taking it? Most people feel fine, but if you get dizziness, wait until it passes before getting behind the wheel.
- What should I do if I vomit within 30minutes of taking a dose? Take the missed dose if you can keep it down; otherwise, contact your doctor for guidance.
Still have doubts? Call your pharmacy or schedule a quick chat with your GP - they can tailor the advice to your health history.

Next Steps and Troubleshooting
If you’re about to start a course, follow the checklist below to keep things smooth:
- Write down the exact dosing schedule on your phone or a sticky note.
- Set a reminder alarm for the same time each day.
- Keep a glass of water handy - the tablet needs enough fluid to dissolve properly.
- If you notice any rash, swelling or trouble breathing, stop the medication and seek emergency care.
- After finishing, note how you felt. This info helps your doctor decide if a different antibiotic might work better next time.
By understanding what Azithromycin DT does, how to take it correctly, and what to watch for, you’re set to treat infections effectively while minimizing risks.