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Dechallenge and Rechallenge in Drug Side Effects: What These Tests Mean
Feb 2 2026 Charlie Hemphrey

Dechallenge and Rechallenge in Drug Side Effects: What These Tests Mean

Dechallenge and rechallenge are key clinical tools used to confirm if a drug caused a side effect. Stopping the drug (dechallenge) and, if safe, restarting it (rechallenge) provide the strongest evidence of causality in pharmacovigilance.

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