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Blockbuster Patent Expirations 2025 and Beyond: What Drugs Lose Protection and When
Feb 13 2026 Ryan Gregory

Blockbuster Patent Expirations 2025 and Beyond: What Drugs Lose Protection and When

In 2025 and beyond, major drugs like Entresto, Eliquis, and Keytruda will lose patent protection, triggering the largest wave of generic and biosimilar competition in pharmaceutical history. This could slash drug costs by up to 90% and reshape healthcare spending.

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